Package | Dosage | Price | Price per Dose | |
---|---|---|---|---|
Dosage: 50mg | ||||
360 pill | 50mg | AUD476.07 | AUD1.32 | |
180 pill | 50mg | AUD245.81 | AUD1.37 | |
120 pill | 50mg | AUD185.13 | AUD1.54 | |
Dosage: 100mg | ||||
360 pill | 100mg | AUD336.05 | AUD0.93 | |
180 pill | 100mg | AUD196.02 | AUD1.09 | |
120 pill | 100mg | AUD152.46 | AUD1.28 | |
90 pill | 100mg | AUD126.01 | AUD1.40 | |
60 pill | 100mg | AUD91.78 | AUD1.54 | |
30 pill | 100mg | AUD54.44 | AUD1.82 |

Nitrofurantoin Monohydrate Description
Overview of Nitrofurantoin Monohydrate
Nitrofurantoin Monohydrate is a widely used antibiotic primarily prescribed for the treatment and prevention of urinary tract infections (UTIs). It belongs to the nitrofuran class of antibiotics, which are known for their broad spectrum of activity against various bacteria. This medication works by interfering with the bacterial enzyme systems, ultimately inhibiting bacterial growth and helping to eliminate infection from the urinary tract. Patients often prefer Nitrofurantoin Monohydrate due to its effectiveness and targeted action, which minimizes systemic side effects often associated with other antibiotics.
How it Works
Nitrofurantoin Monohydrate is rapidly absorbed from the gastrointestinal tract. Once in the bloodstream, it is filtered into the urine, where it exerts its antibacterial effect. It is particularly effective against common pathogens like Escherichia coli, Enterococcus faecalis, and some strains of Staphylococcus saprophyticus. Its mechanism of action involves damaging bacterial DNA, ribosomal proteins, and other critical cellular components. This disruption prevents bacteria from multiplying and helps clear the infection. Due to its concentrated presence in urine, it is highly effective for bladder infections but not suitable for systemic infections.
Usage and Dosage
The typical dosage of Nitrofurantoin Monohydrate varies depending on the severity of the infection, patient age, and overall health condition. For uncomplicated UTIs, the usual adult dose is one capsule taken four times daily for 5 to 7 days. It is recommended to take the medication with food or milk to minimize gastrointestinal discomfort. It is important for patients to complete the full course prescribed by their healthcare provider, even if symptoms improve before the medication is finished. Proper hydration is also advised to promote urine flow and help prevent crystalluria.
Benefits and Effectiveness
Many users report quick symptom relief after starting Nitrofurantoin Monohydrate. It is highly effective in treating uncomplicated UTIs, reducing the risk of recurrence when used appropriately. The medication has a relatively narrow spectrum, which helps target bacteria without significantly affecting the natural flora of the body. Its advantage in outpatient settings makes it a preferred option for managing urinary infections. Moreover, it has a relatively low resistance rate among bacteria, making it a reliable choice in many cases.
Potential Side Effects
While Nitrofurantoin Monohydrate is generally safe when used as directed, some patients may experience side effects. Common adverse reactions include nausea, headache, and gastrointestinal discomfort such as diarrhea or abdominal pain. Rarely, some individuals may develop allergic reactions, presenting as skin rashes or breathing difficulties. Long-term use or high doses can sometimes lead to pulmonary reactions, including cough or shortness of breath, which warrants immediate medical attention. Liver function abnormalities and peripheral neuropathy are other potential but less common side effects.
Precautions and Considerations
Patients with impaired kidney function, especially those with a creatinine clearance below 60 mL/min, should use Nitrofurantoin Monohydrate cautiously, as the drug may accumulate in the body and increase the risk of toxicity. It is also not recommended during pregnancy, particularly near term, due to potential risks to the fetus. Patients with a history of lung disease, nerve disorders, or liver problems should discuss alternative options with their healthcare provider before starting treatment. Regular monitoring, including kidney function tests, can help ensure safe use of this medication.
Final Thoughts
Nitrofurantoin Monohydrate remains a cornerstone in the treatment of urinary tract infections due to its proven efficacy and targeted action against common uropathogens. When used correctly under medical supervision, it provides rapid relief and helps prevent recurrent infections. However, like all antibiotics, it should be used responsibly to reduce the risk of resistance and side effects. Patients are encouraged to follow the prescribed dosage, maintain hydration, and report any unusual symptoms to their healthcare provider promptly.